Injections Of Medication Into Eye

Injections into the vitreous made in order for the medication to directly reach the eye are called intravitreal injections.

Injecting medication into the vitreous has many important advantages. Even an intravitreal medication given in quite a small dose rapidly reaches the desired tissue. Since the application is made into the eye, it has a very small chance of adversely affecting other tissues of the body. The administered amount is very small and the rate of mixing into the bloodstream is quite low. Most patients are afraid of having their eye injected. Actually injection only takes a few seconds and does not cause any pain because it is carried out with very thin needles.  

The operation starts with the application of local anesthetic drops to anesthetize the tissues.  A small amount of anesthetic medication is administered into the injection point with a thin needle. Later the medication is injected. The most important risk of this operation is an intraocular infection (endophthalmitis) which develops very rarely. In order to reduce the risk of injection, it must be carried out under sterile conditions and therefore the eye and its circumference are cleaned with an antiseptic solution and the required preparations are completed. Later the medication is injected into the eye through the sclera. Antibiotic eye drops are administered for a certain period after the operation to eliminate the risk of infection. Although rare, intraocular pressure may increase and the patient may need treatment.

Today intravitreal injections are mostly used to treat wet type age-related macular degeneration (yellow spot disease). In this disease, medications called anti-VEGF are injected into the eye to dry the abnormal vessels in the macula. Intraocular injections are also applied for the treatment of severe intraocular infections such as macular edema which develops due to diabetes or obstructions in the retinal veins and endophthalmitis, and effective results are obtained.